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December 2002

Success in Battle against Botulism in Swans

Index to The Regal Swan Project

Dr. Geoffrey R. Gardner

Dr. Geoffrey R. Gardner, a Lakeland Veterinarian and researcher for The
Regal Swan™ vaccinates an English Mute Swan in Lakeland, Florida.

© Photo by Shirley Bolin, The Regal Swan™. All rights reserved.

Florida Researchers Confirm Vaccine Used Against Botulism In Swans Highly Successful.

Titer tests conducted over three-year period confirm results and establish vaccination protocols.


ORLANDO, Florida -- Six Florida researchers confirmed today that a vaccine used against botulism in swans has been highly successful in showing a sustained level of antibody response. The group's research offers the first real hope that a vaccine against the deadly Clostridia bacterial toxin can protect the world's largest waterfowl.

The three-year scientific study and more than 20-years clinical trial of vaccine usage in swans produced no detrimental side effects or deaths in inoculated swans. The Regal Swan™, a Florida based group, conducted the study while Pfizer Animal Health sponsored the research by providing laboratory and testing assistance. The titer tests were conducted by Rod Little, Pfizer Global Manufacturing.

Current vaccination protocols were established based on the scientific research gathered during the course of the study. The data collected indicated that an additional inoculation would be beneficial to vaccinated cygnets between five and six months of age to enhance and maintain antibody levels. The use of the Pfizer Ultrabac® CD vaccine for use in swans remains an off-label application.

Prior to the research, no proven vaccine existed for the deadly botulism toxin. In the early 80's, a Lakeland, Florida veterinarian, Wade G. Gardner, D.V.M., pioneered the use of the Pfizer Ultrabac® CD vaccine in swans to mitigate swan deaths due to botulism at Lake Morton. Some of Lakeland's English Mute Swans are direct descendants of a mating pair of English Mute Swans donated to the city by Her Majesty Queen Elizabeth II in 1957.

Dr. Gardner, now retired, knew that an established vaccine was available for Clostridial diseases in cows. Dr. Gardner theorized that the symptoms of Clostridial diseases could mimic botulism. He began experimental inoculation in the Lakeland swans using the Ultrabac® CD vaccine. Until the Florida group's research, no titer testing existed in swans and the scientific investigation into the swans' antibody response to the vaccine had not been documented. Initial vaccination protocols were set by Dr. Wade Gardner through his clinical applications. As a result, Lakeland swan deaths due to botulism were mitigated for more than 20 years.

Dr. Wade G. Gardner pioneer

Left to right: Dr. Wade G. Gardner, retired Lakeland veterinarian who pioneered the use of the vaccine against botulism. Sheila Bolin, swan keeper Orange Lake Resort & Country Club in Orlando, Florida and researcher for The Regal Swan™ and Dr. Geoffrey Gardner, Lakeland veterinarian, Lakeland Veterinarian Hospital, Lakeland, Florida and researcher for The Regal Swan™, son of Dr. Wade G. Gardner.

© Photo by Shirley Bolin, The Regal Swan™. All rights reserved.

Three swan sites were used in the testing protocols: Lake Morton, a 40-acre lake in Lakeland, Florida, served as the natural lake test site while the eight-acre Fountain Lake at Orange Lake Resort & Country Club in Orlando, Florida, served as the man-made test site. Orange Lake is an 1,100 acre resort developed by Kemmons Wilson, the founder of Holiday Inns®. The control test site for the research was located at Memphis Zoo in Memphis, Tennessee.

The Regal Swan™ researchers were: Geoffrey R. Gardner, D.V.M., Lakeland Veterinary Hospital, Lakeland, Florida; Christopher W. Brown, D.V.M., Central Florida relief veterinarian, Orlando, Florida; Fanchon F. Funk, Ed.D., associate professor, Florida State University, Tallahassee, Florida; Sheila A. Bolin, M.S., swan keeper, Orange Lake Resort & Country Club, Orlando, Florida; Rebecca Webb Wilson, J.D., professional photographer and lifetime trustee of the Memphis Zoological Society, Memphis, Tennessee; and Shirley A. Bolin, A.G.S., head photographer and staff writer, Orange Lake Resort & Country Club, Orlando, Florida.

Photo of left to right: Rebecca Webb Wilson, photographer and researcher for The Regal Swan™, her husband Spence Wilson, chairman of the board, Orange Lake Resort & Country Club, Orlando, Florida. Spence's father, Kemmons Wilson, is the founder of Orange Lake and Holiday Inn®. Dr. Christopher W. Brown, veterinarian and researcher for The Regal Swan™ holding an English Mute Swan cygnet from Orange Lake.

© Photo by Shirley Bolin, The Regal Swan™. All rights reserved.

Additionally, the six-team members compiled crucial information on worldwide swan mortality through the efforts of Roger Cullingham, (theroyalwindsorwebsite.com by Thamesweb), Windsor, England; Her Majesty's Swan Warden, Dr. Christopher Perrins, director of The Earl Grey Institute of Ornithology, Oxford University, London, England; Her Majesty's Swan Marker, David Barber; Dorothy Beeson, founder, The Swan Sanctuary, Egham, England; Steve Knight, trustee, The Swan Sanctuary, Egham, England; Martin Brown, animal health officer, Wildfowl and Wetlands Trust Fund, Slimbridge, England; Dr. Vladimir Spitsin, director of the Moscow Zoo, Moscow, Russia; Sergei Popov, head of research at the Moscow Zoo, Moscow, Russia; and Dr. Nikolai Puchkov, The Russian Academy of Sciences, Moscow, Russia.

Fanchon F Funk

Fanchon F. Funk, Ed.D. associate professor, Florida State University, Tallahassee, Florida and a researcher for The Regal Swan™.

© Photo by Shirley Bolin, The Regal Swan™. All rights reserved.


Shirley Bolin, photographer and researcher for The Regal Swan™ holding a Lakeland English Mute Swan.

© Photo by Shirley Bolin, The Regal Swan™. All rights reserved.

Dr. Christopher W. Brown takes a blood sample

Dr. Christopher W. Brown takes a blood sample from an Orange Lake
English Mute cygnet as associate swan keeper Kathleen Sterling holds
the young swan.

© Photo by Shirley Bolin, The Regal Swan™. All rights reserved.

Rebecca Webb Wilson, photographer and researcher for The Regal Swan™
with an Orange Lake English Mute Swan.

© Photo by Shirley Bolin, The Regal Swan™. All rights reserved.

Sponsors include:
Pfizer Animal Health, Orange Lake Resort & Country Club, City of Lakeland, Florida, Lakeland Veterinary Hospital, Antech Diagnostic Labs, Inc., American Camper, Blitz® USA, Bushnell Sports Optics Worldwide, Cobra Electronics, Hunt Manufacturing Company, IQ Scientific Instruments, Kaz Incorporated, Lab Essentials, Inc., The National High Magnetic Laboratory, Florida State University; The Memphis Zoo, Orlando Science Center, theroyalwindsorwebsite.com by Thamesweb, Windsor, England; Sharn Veterinary, Inc., The Sports Authority, Timex®, VetCare, Vicks Company and Western Pest Services.

For further information on the 'Regal Swan Project', contact Sheila Bolin, Orange Lake Resort & Country Club (Email: Bolin.S@att.net) Telephone: (407) 931-6838 or Dr. Geoffrey Gardner at (941) 665-1811.

 

A note from The Regal SwanTeam

The Regal Swan would like to express its sincere appreciation and thanks to the following:

Her Majesty Queen Elizabeth II for her kind donation of swans to the city of Lakeland in 1957, which made this research possible.

Her Majesty's Swan Warden, Dr. Christopher Perrins and Her Majesty's Swan Marker, Mr. David Barber, for helping to compile critical information necessary to conduct the research.

Mr. Roger Cullingham, Thamesweb and The Royal Windsor Website for helping
to gather contacts and information to compile the data. We are forever grateful.

With sincere thanks and appreciation, Dr. Wade G. Gardner for having the courage to use this innovative idea to quell swan deaths, and most importantly, our deepest thanks to the Kemmons Wilson family. Without their unwavering support and help this project would not have been possible.

The Regal Swan
December 2002   

A note from the Editor, Thamesweb, Windsor.

Many people, not just here in Windsor or along the River Thames, but around the world, will be particularly pleased and relieved to hear of this success by the team in Florida, USA.

The grace and beauty of a swan enhances any stretch of water and the successful outcome of this research will dramatically reduce the sad losses that occur from time to time due to botulism in the swan population.

Swans on the Thames are synonymous with Windsor and so we are particularly delighted with this news. We extend our sincerest congratulations to the team in Florida, its supporters and sponsors for a job very well done. I know a lot of swans down by the river who will be very pleased to hear the news too!

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